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A 6-year-old, spayed female rottweiler was presented for facial enlargement from swelling of the maxilla and mandible. The dog was fed a homemade diet deficient in calcium and vitamin D, suggesting that rubber jaw syndrome was a secondary nutritional disorder. Radiographic and tomodensitometric examinations revealed diffuse bone resorption in the skull. The plasma parathormone concentration was high, and serum 25-hydroxycholecalciferol concentration was low. Based on these findings, nutritional calcium and vitamin D deficiency associated with secondary hyperparathyroidism was diagnosed. Dietary correction resulted in clinical and biological improvement, with an increase in skull mineralization.

Citation

Pauline de Fornel-Thibaud, Géraldine Blanchard, Laurence Escoffier-Chateau, Sophie Segond, Franck Guetta, Dominique Begon, Françoise Delisle, Dan Rosenberg. Unusual case of osteopenia associated with nutritional calcium and vitamin D deficiency in an adult dog. Journal of the American Animal Hospital Association. 2007 Jan-Feb;43(1):52-60

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PMID: 17209086

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