Department of Medicine and Microbiology, Columbia University, New York, NY 10032, USA. rc645@columbia.edu
Immunity 2007 JanThe immunosuppressive mechanism of action of intravenous immune globulin (IVIG) has remained enigmatic despite the many years of clinical experience in the treatment of autoimmunity. In this issue of Immunity, Park-Min et al. demonstrate that IVIG engagement of Fcgamma RIII receptor on monocytes inhibits the cellular response to interferon-gamma.
Raphael Clynes. IVIG therapy: interfering with interferon-gamma. Immunity. 2007 Jan;26(1):4-6
PMID: 17241954
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