Late onset congenital adrenal hyperplasia due to 21-hydroxylase deficiency presenting as isolated premature thelarche.

Department of Pediatrics, Division of Pediatric Endocrinology, Marshfield Clinic, Marshfield, WI 54449, USA. zador.ivan@marshfieldclinic.org

Journal of pediatric endocrinology & metabolism : JPEM 2007 Jan

filter terms:

A 19 month-old female presented with isolated premature thelarche and significantly advanced bone age. The underlying cause of this clinical presentation was found to be late-onset congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency. To the author's knowledge this is the first reported case of late-onset CAH presenting as isolated premature thelarche.

Citation

Ivan Zador. Late onset congenital adrenal hyperplasia due to 21-hydroxylase deficiency presenting as isolated premature thelarche. Journal of pediatric endocrinology & metabolism : JPEM. 2007 Jan;20(1):87-90