Zollinger Ellison syndrome, treated with lansoprazole, during pregnancy.

Amit Mayer, Eyal Sheiner, Gershon Holcberg

Department of Obstetrics and Gynecology, Faculty of Health Sciences, Soroka University Medical Center, Ben Gurion University of the Negev, P.O. Box 151, Beer-Sheva 84101, Israel. amayer@bgumail.bgu.ac.il

Archives of gynecology and obstetrics 2007 Aug

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Zollinger Ellison syndrome (ZES), an ulcerative disease of the upper gastrointestinal tract that involves the production of high levels of gastrin and gastric acid, is a rare, symptomatic, endocrine neoplastic disease. We report a rare case of gastrinoma that was first diagnosed during pregnancy in which the primary tumor was located in the liver. The ZES was well controlled with Zoton (Lansoprazole) following surgery. The patient had an uneventful pregnancy and delivery without significant complications. The present case suggests that treatment with Zoton for ZES during pregnancy is safe and effective.

Citation

Amit Mayer, Eyal Sheiner, Gershon Holcberg. Zollinger Ellison syndrome, treated with lansoprazole, during pregnancy. Archives of gynecology and obstetrics. 2007 Aug;276(2):171-3