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1,5-anhydro-D-fructose was efficiently prepared from D-fructose via regiospecific 1,5-anhydro ring formation of 2,3-O-isopropylidene-1-O-methyl(tolyl)sulfonyl-D-fructopyranose and subsequent deprotection.

Citation

Gyula Dekany, Inge Lundt, Fabian Niedermair, Sabine Bichler, Josef Spreitz, Friedrich K Fitz Sprenger, Arnold E Stütz. 1,5-anhydro-D-fructose from D-fructose. Carbohydrate research. 2007 Jul 2;342(9):1249-53

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PMID: 17368437

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