Bioactive compounds from Bauhinia purpurea possessing antimalarial, antimycobacterial, antifungal, anti-inflammatory, and cytotoxic activities.

Surat Boonphong, Pakawan Puangsombat, Apiwat Baramee, Chulabhorn Mahidol, Somsak Ruchirawat, Prasat Kittakoop

Department of Chemistry, Faculty of Science, Chiang Mai University, Chiang Mai, Thailand.

Journal of natural products 2007 May

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Eleven new secondary metabolites (1-11), together with two known flavanones (12 and 13) and five known bibenzyls (14-18), were isolated from the root extract of Bauhinia purpurea. New compounds include eight dihydrodibenzoxepins (1-8), a dihydrobenzofuran (9), a novel spirochromane-2,1'-hexenedione (10), and a new bibenzyl (11). Antimycobacterial, antimalarial, antifungal, cytotoxic, and anti-inflammatory activities of the isolated compounds are reported, and biosynthetic pathways of these compounds are also discussed.

Citation

Surat Boonphong, Pakawan Puangsombat, Apiwat Baramee, Chulabhorn Mahidol, Somsak Ruchirawat, Prasat Kittakoop. Bioactive compounds from Bauhinia purpurea possessing antimalarial, antimycobacterial, antifungal, anti-inflammatory, and cytotoxic activities. Journal of natural products. 2007 May;70(5):795-801