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Cephazolin sodium prepared with four different solutions (NaCl 0.9%, Protagent, Liquifilm and phosphate buffer) to be used as eye drops, was evaluated as to its physicochemical features at +4 degrees C, +37 degrees C and at room temperature and its activity in terms of minimal inhibition concentration. In conclusion, cephazolin sodium prepared with artificial tears at acidic pH can be kept for 3 days at room temperature and at +4 degrees C without any loss of its activity.

Citation

N Yildirim, S Topbaş, G Usluer, I Ozgüneş, H Başmak, S Yurdakul. Stability of cefazolin sodium as eyedrops in various solutions]. Mikrobiyoloji bülteni. 1991 Jul;25(3):272-6

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PMID: 1762595

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