Chemical constituents from leaves of Celastrus gemmatus Loes.

Wei-Sheng Feng, Zhi-You Hao, Xiao-Ke Zheng, Hai-Xue Kuang

Henan University of Traditional Chinese Medicine, Zhengzhou 450008, China. fwsh@hactcm.edu.cn

Yao xue xue bao = Acta pharmaceutica Sinica 2007 Jun

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To study the chemical constituents from the leaves of Celastrus gemmatus Loes., chromatographic methods were used to isolate and purify the chemical constituents, their structures were elucidated by the physiochemical characteristics and spectral data. Nine compounds were obtained and identified as (-)-massoniresinol 3a-O-beta-D-glucopyranoside (1), ambrosidine (2), isolariciresinol 9-O-beta-D-glucopyranoside (3), kaempferol 3-O-beta-D-glucopyranoside (astragalin) (4), kaempferol 3-O-rutinoside (5), kaempferol 3-O-neohesperidoside (6), apigenin 7-O-beta-D-glucuronide (7), apigenin 7-O-beta-D-glucuronide methyl ester (8) and D-sorbitol (9). Compound 1 is a new compound, the others are isolated from this genus for the first time, and this is the first time to report lignan compounds from genus Celastrus.

Citation

Wei-Sheng Feng, Zhi-You Hao, Xiao-Ke Zheng, Hai-Xue Kuang. Chemical constituents from leaves of Celastrus gemmatus Loes. Yao xue xue bao = Acta pharmaceutica Sinica. 2007 Jun;42(6):625-30