Drosophila Ten-a is a maternal pair-rule and patterning gene.

Nadya Rakovitsky, Yosef Buganim, Tomer Swissa, Yael Kinel-Tahan, Shirly Brenner, Malkiel A Cohen, Anna Levine, Ron Wides

The Mina and Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan 52900, Israel.

Mechanisms of development 2007 Nov-Dec

filter terms:

The Ten-a gene of Drosophila melanogaster encodes several alternative variants of a full length member of the Odz/Tenm protein family. A number of Ten-a mutants created by inexact excisions of a resident P-element insertion are embryonic lethal, but show no pair-rule phenotype. In contrast, these mutants, and deficiencies removing Ten-a, do enhance the segmentation phenotype of a weak allele of the paralog gene odz (or Ten-m) to the odz amorphic phenotype. Germ line clone derived Ten-a(-) embryos display a pair-rule phenotype which phenocopies that of odz. Post segmentation eye patterning phenotypes of Ten-a mutants establish it as a pleiotropic patterning co-partner of odz.

Citation

Nadya Rakovitsky, Yosef Buganim, Tomer Swissa, Yael Kinel-Tahan, Shirly Brenner, Malkiel A Cohen, Anna Levine, Ron Wides. Drosophila Ten-a is a maternal pair-rule and patterning gene. Mechanisms of development. 2007 Nov-Dec;124(11-12):911-24