Genetic imprinting and embryonic development].

Li-jun Yin, He-feng Huang

Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 2007 Sep

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Erasure, establishment and maintenance of genetic imprinting are indispensable for normal embryonic development. All these processes depend on accurate expression and intimate cooperation of kinds of DNA methyltransferases. Many genetic syndromes and embryo developmental anomalies are caused by abnormality of genetic imprinting. Genetic imprinting is important for the nucleus totipotential of primordial germ cell, maturation of gamete,growth and development of embryo, structure and function of placenta as well as postnatal growth and development of individuals.

Citation

Li-jun Yin, He-feng Huang. Genetic imprinting and embryonic development]. Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences. 2007 Sep;36(5):509-14