2',3'-isopropylidene group, a molecular scaffold to study the activity of adenosine and adenylate deaminase on adenosine analogues modified in the ribose moiety.

Pierangela Ciuffreda, Laura Alessandrini, Enzo Santaniello

Dipartimento di Scienze Precliniche LITA Vialba, Università degli Studi di Milano, via G.B. Grassi 74, 20157 Milan, Italy. pierangela.ciuffreda@unimi.it

Nucleosides, nucleotides & nucleic acids 2007

filter terms:

2 ',3 '-Isopropylidene group can be used as a molecular scaffold for the introduction of modifications at 5 ' and 1 ' positions of adenosine and these modified nucleosides are used to evaluate the biocatalytic activity of adenosine and adenylate deaminase.

Citation

Pierangela Ciuffreda, Laura Alessandrini, Enzo Santaniello. 2',3'-isopropylidene group, a molecular scaffold to study the activity of adenosine and adenylate deaminase on adenosine analogues modified in the ribose moiety. Nucleosides, nucleotides & nucleic acids. 2007;26(10-12):1311-3