Expression of trophinin in human oocytes and preimplantation embryos].

Hua-Yun Wang, Fu-Qi Xing, Shi-Ling Chen

Department of Obstetrics and Gynecology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.

Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2008 Jan

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To investigate the significance of trophinin expression in human oocytes and preimplantation embryos. The expression of trophinin in 9 human oocytes, 16 blastomeres and 12 blastocysts were detected by indirect immunofluorescence assay and observed under laser scanning confocal microscope. Human oocytes, blastomeres and blastocysts were all positive for trophinin expression, and the positivity intensified significantly in the course of the embryonic development (P<0.05). Trophinin may play an important role in human embryo implantation by mediating homophilic adhesion between the embryo and the endometrium during the implantation window.

Citation

Hua-Yun Wang, Fu-Qi Xing, Shi-Ling Chen. Expression of trophinin in human oocytes and preimplantation embryos]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University. 2008 Jan;28(1):122-4