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A tributyltin (TBT) luxAB transcriptional fusion in Escherichia coli revealed that a TBT-activated promoter is located upstream of two cotranscribed orphan genes, ygaV and ygaP. We demonstrate that transcription from the promoter upstream of ygaVP is constitutive in a ygaVP mutant, suggesting that YgaV is an autoregulated, TBT-inducible repressor.

Citation

Hervé Gueuné, Marie-José Durand, Gérald Thouand, Michael S DuBow. The ygaVP genes of Escherichia coli form a tributyltin-inducible operon. Applied and environmental microbiology. 2008 Mar;74(6):1954-8

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PMID: 18245262

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