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The interaction between Cu(II) and the rat amyloid beta (1-28) fragment in micellar solutions at pH 7.5 was investigated by CD and NMR spectroscopy; the proton-copper distances were used in restrained molecular dynamics simulations to obtain a structural model of the Cu(II) complex.


Elena Gaggelli, Zbigniew Grzonka, Henryk Kozłowski, Caterina Migliorini, Elena Molteni, Daniela Valensin, Gianni Valensin. Structural features of the Cu(II) complex with the rat Abeta(1-28) fragment. Chemical communications (Cambridge, England). 2008 Jan 21(3):341-3

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PMID: 18399201

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