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Cuminaldehyde (4-isopropylbenzaldehyde) suppressed melanin formation in cultured murine B16-F10 melanoma cells in a dose-dependent decrease up to 0.25 mm without affecting cell growth. Approximately 30% suppression in melanin production resulted when the cells were cultured with 0.25 mm of cuminaldehyde. This activity was not noticeable with cultured human A375 melanoma cells. Copyright (c) 2008 John Wiley & Sons, Ltd.


Teruhiko Nitoda, Maria D Fan, Isao Kubo. Effects of cuminaldehyde on melanoma cells. Phytotherapy research : PTR. 2008 Jun;22(6):809-13

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PMID: 18412105

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