Effects of cuminaldehyde on melanoma cells.

Department of Environmental Science, Policy and Management, University of California, Berkeley, California 94720, USA. nitoda@cc.okayama-u.ac.jp

Phytotherapy research : PTR 2008 Jun

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Cuminaldehyde (4-isopropylbenzaldehyde) suppressed melanin formation in cultured murine B16-F10 melanoma cells in a dose-dependent decrease up to 0.25 mm without affecting cell growth. Approximately 30% suppression in melanin production resulted when the cells were cultured with 0.25 mm of cuminaldehyde. This activity was not noticeable with cultured human A375 melanoma cells. Copyright (c) 2008 John Wiley & Sons, Ltd.