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Five new pyronane-type monocyclic monoterpenoids, jasminodiol (1), jasminoside H (6), 6'-O-sinapoyljasminoside A (7), 6'-O-sinapoyljasminoside C (8), and jasminoside I (9), together with four known analogues, were isolated from the fruit of Gardenia jasminoides. The structures of the new metabolites were characterized using spectroscopic data, and the absolute configurations of 1, 6, and 7 were established using circular dichroism (CD) analysis. Compound 1 showed tyrosinase inhibitory activity (IC 50 2.2 mM).

Citation

Quan Cheng Chen, UiJoung Youn, Byung-Sun Min, KiHwan Bae. Pyronane monoterpenoids from the fruit of Gardenia jasminoides. Journal of natural products. 2008 Jun;71(6):995-9

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PMID: 18505286

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