In vitro activity of the quinolone WCK 771 against recent U.S. hospital and community-acquired Staphylococcus aureus pathogens with various resistance types.

Sachin S Bhagwat, Pamela McGhee, Klaudia Kosowska-Shick, Mahesh V Patel, Peter C Appelbaum

Antimicrobial agents and chemotherapy 2009 Feb

filter terms:

WCK 771 demonstrated MIC(50) and MIC(90)s of 0.03 and 1 microg/ml, respectively, against 297 recent U.S. community-acquired and hospital strains of Staphylococcus aureus, irrespective of quinolone or glycopeptide resistance. Against quinolone-resistant strains, MIC(90)s of WCK 771 and moxifloxacin were 1 and 16 microg/ml, respectively.

Citation

Sachin S Bhagwat, Pamela McGhee, Klaudia Kosowska-Shick, Mahesh V Patel, Peter C Appelbaum. In vitro activity of the quinolone WCK 771 against recent U.S. hospital and community-acquired Staphylococcus aureus pathogens with various resistance types. Antimicrobial agents and chemotherapy. 2009 Feb;53(2):811-3