Correlation Engine 2.0
Clear Search sequence regions


Sizes of these terms reflect their relevance to your search.

An efficient one-pot oxidative decarboxylation-Friedel-Crafts reaction of acyclic alpha-amino acid derivatives with electron-rich aromatic compounds is reported. The reaction is activated by the combination of iodobenzene diacetate, iodine and iron dust, resulting in a mild and simple reaction system. The use of iron avoids the oxidation of aromatic compounds, and in situ generation of Fe(III) salts to promote the Friedel-Crafts reaction avoids the use of the highly hygroscopic FeCl(3).

Citation

Renhua Fan, Weixun Li, Bing Wang. A one-pot oxidative decarboxylation-Friedel-Crafts reaction of acyclic alpha-amino acid derivatives activated by the combination of iodobenzene diacetate/iodine and iron dust. Organic & biomolecular chemistry. 2008 Dec 21;6(24):4615-21

Expand section icon Mesh Tags

Expand section icon Substances


PMID: 19039371

View Full Text