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Two new antitumor trimeric hydrolyzable tannins, woodfordin D (5) and oenothein A (13), were isolated from the dried flowers of Woodfordia fruticosa, and their macrocyclic structures, which have a novel constituent unit (woodfordinoyl group) connecting the monomers, have been elucidated on the basis of spectral and chemical evidence. Oenothein A (13) was also isolated from the leaves of Oenothera biennis.

Citation

T Yoshida, T Chou, M Matsuda, T Yasuhara, K Yazaki, T Hatano, A Nitta, T Okuda. Woodfordin D and oenothein A, trimeric hydrolyzable tannins of macro-ring structure with antitumor activity. Chemical & pharmaceutical bulletin. 1991 May;39(5):1157-62

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PMID: 1913994

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