Sequence selective dual-emission detection of (i, i + 1) bis-phosphorylated peptide using diazastilbene-type Zn(II)-Dpa chemosensor.

Yoshiyuki Ishida, Masa-aki Inoue, Tomonori Inoue, Akio Ojida, Itaru Hamachi

Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Katsura Campus, Kyoto, Japan.

Chemical communications (Cambridge, England) 2009 May 28

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This paper describes a new fluorescent chemosensor for phosphorylated peptide, which comprises a rigid trans-4,4'-diazastilbene and two Zn(II)-Dpa (2,2'-dipicolylamine) units; this chemosensor sequence-selectively binds to a (i, i + 1) bis-phosphorylated peptide and displays a dual-emission fluorescence change.

Citation

Yoshiyuki Ishida, Masa-aki Inoue, Tomonori Inoue, Akio Ojida, Itaru Hamachi. Sequence selective dual-emission detection of (i, i + 1) bis-phosphorylated peptide using diazastilbene-type Zn(II)-Dpa chemosensor. Chemical communications (Cambridge, England). 2009 May 28(20):2848-50