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We reported 3 cases of the uncommon type of persistent gastrointestinal bleeding during anticoagulation therapy due to cardiovascular disorders or collagen disease. Endoscopic observation showed non pulsatile active bleeding from apparently normal mucosa, without any ulcer or obvious vascularectasia. The outflow of bleeding was string-like and continuous. Based on previous reports, we considered the possibly of these cases unique bleeding angiodysplasia and angiodysplasia during anticoagulation therapy. The frequency of this type of bleeding may increase, as anticoagulation therapy has become more common. We should pay attention to such lesions when we treat gastrointestinal bleeding.

Citation

Takeshi Sato, Hiroaki Takeda, Tomohiko Orii, Sayaka Otake, Shoichiro Fujishima, Shoichi Nishise, Yu Sasaki, Sumio Kawata. Non pulsatile active bleeding from the gastrointestinal mucosa without ulceration during anticoagulation therapy -consideration on bleeding from angiodysplasia during anticoagulation therapy-]. Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology. 2009 Jun;106(6):813-9

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PMID: 19498313

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