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A novel alkaloid, named hypodematine, was isolated from Hypodematium sinense Iwatsuki (belonging to the lypterdaceae). Its structure has been elucidated to have a novel skeleton of benzo-aza-cyclooctatetraene with a phenyl substitution by means of the 1H-1H COSY, 1H-13C COSY and long-range 1H-13C COSY spectroscopy.

Citation

Y M Chen, Y H Lu, Y J Chen, C S Ma, D Q Yu. Application of 2D-NMR techniques in the structure determination of hypodematine]. Yao xue xue bao = Acta pharmaceutica Sinica. 1991;26(2):123-7

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PMID: 1950567

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