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From the discovery of the regulation of bone remodelling by leptin, much attention has been focused on neurogenic control of bone remodelling. Various hypothalamic neuropeptides, which are involved in appetite regulation, are now revealed to be important regulators of bone remodelling. More recently, neurotransmitters, such as serotonin or catecholamines, are proven to be bone remodelling regulators.

Citation

Shu Takeda. Hormones and osteoporosis update. Regulation of bone remodeling by neuropeptides and neurotransmitters]. Clinical calcium. 2009 Jul;19(7):990-6

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PMID: 19567996

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