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The readily available and enzymatically derived cis-1,2-dihydrocatechol 3 has been converted, over 15 steps, into (+)-amabiline, the non-natural enantiomeric form of a crinine-type alkaloid.

Citation

Alison D Findlay, Martin G Banwell. A chemoenzymatic total synthesis of (+)-amabiline. Organic letters. 2009 Jul 16;11(14):3160-2

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PMID: 19586069

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