Residual and recurrent gastrointestinal stromal tumors with KIT mutations: findings at first follow-up CT after imatinib treatment.

The purpose of this study was to correlate findings on the first follow-up CT after treatment with imatinib in patients with residual or recurrent gastrointestinal stromal tumors (GISTs) with the different types of KIT mutation present at initial resection. Residual and recurrent GISTs with KIT mutation of exon 11 deletion more frequently showed both tumor shrinkage and cystic change on 2-month follow-up CT images after the start of imatinib treatment than did other mutation types.

Citation

Dongil Choi, Eun Young Yoo, Kyoung-Mee Kim, Tae Sung Sohn, Won Jae Lee, Ji Young Lee, Ilsoo Chang. Residual and recurrent gastrointestinal stromal tumors with KIT mutations: findings at first follow-up CT after imatinib treatment. AJR. American journal of roentgenology. 2009 Aug;193(2):W100-5

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PMID: 19620409

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