Multiresponsive switchable diarylethene and its application in bioimaging.

Xijun Piao, Ying Zou, Junchen Wu, Chunyan Li, Tao Yi

Department of Chemistry and Laboratory of Advanced Materials, Fudan University, Shanghai 200433, PR China.

Organic letters 2009 Sep 3

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A multiresponsive fluorescent switch based on diarylethene and terpyridine units was developed. It exhibits effective switchable fluorescence which can be controlled by UV/visible light or metal ion/EDTA in solution. More importantly, having low toxicity, it can enter live cells as a fluorescent probe and can also serve as a detector for the biological process of metal ion transmembrane transport.

Citation

Xijun Piao, Ying Zou, Junchen Wu, Chunyan Li, Tao Yi. Multiresponsive switchable diarylethene and its application in bioimaging. Organic letters. 2009 Sep 3;11(17):3818-21