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A multiresponsive fluorescent switch based on diarylethene and terpyridine units was developed. It exhibits effective switchable fluorescence which can be controlled by UV/visible light or metal ion/EDTA in solution. More importantly, having low toxicity, it can enter live cells as a fluorescent probe and can also serve as a detector for the biological process of metal ion transmembrane transport.


Xijun Piao, Ying Zou, Junchen Wu, Chunyan Li, Tao Yi. Multiresponsive switchable diarylethene and its application in bioimaging. Organic letters. 2009 Sep 3;11(17):3818-21

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PMID: 19658406

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