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In this issue, Liu et al. (2009) report that maxicircle DNA copy number in trypanosomes is regulated by proteolysis of a helicase; the complex kinetoplast DNA system yields a clear view of how mitochondrial DNA replication can be regulated.


Michele M Klingbeil, Theresa A Shapiro. Unraveling the secrets of regulating mitochondrial DNA replication. Molecular cell. 2009 Aug 28;35(4):398-400

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PMID: 19716784

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