Small invasive ductal adenocarcinoma of the pancreas associated with lymphoplasmacytic sclerosing pancreatitis.

Utaroh Motosugi, Tomoaki Ichikawa, Hiroshi Yamaguchi, Tadao Nakazawa, Ryohei Katoh, Jun Itakura, Hideki Fujii, Tadashi Sato, Tsutomu Araki, Michio Shimizu

Department of Radiology, University of Yamanashi, Chuo, Japan. utarohmotosugi@nifty.com

Pathology international 2009 Oct

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An asymptomatic 59-year-old man underwent pancreatoduodenectomy for a pancreatic mass that was discovered during a health check-up. Histopathology indicated typical features of lymphoplasmacytic sclerosing pancreatitis (LPSP) or autoimmune pancreatitis along with the presence of abundant IgG4-positive plasma cells throughout the mass. A small invasive ductal adenocarcinoma was observed in the center of the area affected by LPSP. The present case suggests that LPSP may be closely related to carcinogenesis of the pancreas.

Citation

Utaroh Motosugi, Tomoaki Ichikawa, Hiroshi Yamaguchi, Tadao Nakazawa, Ryohei Katoh, Jun Itakura, Hideki Fujii, Tadashi Sato, Tsutomu Araki, Michio Shimizu. Small invasive ductal adenocarcinoma of the pancreas associated with lymphoplasmacytic sclerosing pancreatitis. Pathology international. 2009 Oct;59(10):744-7