Research on piezoelectric protein sensor array for rapid detecting HIV(1+2) antibody].

Ying Wen, Guiqiu Shan, Jinhui Pu, Zhongming Liu

Department of Blood Transfusion, General Hospital of Guangzhou Command, Guangzhou 510010, China. yingw07@126.com

Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi 2009 Aug

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To research piezoelectric immunosensor array for rapid detecting HIV(1+2), piezoelectric immunosensor array matrix was designed. HIV(1+2)C1 antigen was immobilized onto the silver electrodes of quartz-crystal microbalance, which was modified with adsorption and cross-linked method. In the clean air flow and monitoring environment, standard quality control and clinical serum sample were detected. The linear range for the measurement of HIV(1+2) was 0.01-0.2 NCU/ml. The sensitivity, specificity and accuracy of HIV(1+2) piezoelectric protein sensor array were 91.7%, 93.3% and 92.7% respectively.

Citation

Ying Wen, Guiqiu Shan, Jinhui Pu, Zhongming Liu. Research on piezoelectric protein sensor array for rapid detecting HIV(1+2) antibody]. Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi. 2009 Aug;26(4):883-5