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A label-free adenosine sensor with emissive response is designed based on an AP site-containing aptamer/DNA duplex and a small fluorescent molecule 2-amino-5,6,7-trimethyl-1,8-naphthyridine (ATMND).

Citation

Zhiai Xu, Kotaro Morita, Yusuke Sato, Qing Dai, Seiichi Nishizawa, Norio Teramae. Label-free aptamer-based sensor using abasic site-containing DNA and a nucleobase-specific fluorescent ligand. Chemical communications (Cambridge, England). 2009 Nov 14(42):6445-7

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PMID: 19841804

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