Signaling by neuronal tyrosine kinase receptors: relevance for development and regeneration.

Barbara Hausott, Isil Kurnaz, Srecko Gajovic, Lars Klimaschewski

Division of Neuroanatomy, Medical University Innsbruck, Muellerstrasse 59, Innsbruck, Austria.

Anatomical record (Hoboken, N.J. : 2007) 2009 Dec

filter terms:

Receptor tyrosine kinase activation by binding of neurotrophic factors determines neuronal morphology and identity, migration of neurons to appropriate destinations, and integration into functional neural circuits as well as synapse formation with appropriate targets at the right time and at the right place. This review summarizes the most important aspects of intraneuronal signaling mechanisms and induced gene expression changes that underlie morphological and neurochemical consequences of receptor tyrosine kinase activation in central and peripheral neurons. (c) 2009 Wiley-Liss, Inc.

Citation

Barbara Hausott, Isil Kurnaz, Srecko Gajovic, Lars Klimaschewski. Signaling by neuronal tyrosine kinase receptors: relevance for development and regeneration. Anatomical record (Hoboken, N.J. : 2007). 2009 Dec;292(12):1976-85