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Thrombotic thrombocytopenic purpura (TTP) is an uncommon and potentially fatal syndrome which is due to either congenital or acquired deficiency of the ultra large von Willbrand's factor (ULVWF) cleavage protease. It is characterized by mechanical micro angiopathic hemolytic anemia, and organ dysfunctions.


T M Ibrahim, N Iheonunekwu. Thrombotic thrombocytopenic purpura associated with Staphylococcus aureus endocarditis in a diabetic with furunculosis. Nigerian journal of medicine : journal of the National Association of Resident Doctors of Nigeria. 2009 Oct-Dec;18(4):422-3

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PMID: 20120151

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