Mohammad Reza Sharifmoghadam, Nagore de Leon, Marta Hoya, María-Angeles Curto, María-Henar Valdivieso
Departamento de Microbiología y Genética/Instituto de Microbiología Bioquímica, Universidad de Salamanca/CSIC, Salamanca, Spain.
FEMS microbiology letters 2010 AprIn this paper we show that in Schizosaccharomyces pombe, mating-specific cell adhesion is dependent on the exocyst subunit Sec8p, but independent of the exocyst subunit Exo70p. In the absence of Exo70p, the forespore membrane does not develop properly and the leading edge protein Meu14p is abnormally distributed. Additionally, the spindle pole body is aberrant in a significant number of exo70Delta asci. In both the sec8-1 and the exo70Delta mutants, the development of the spore cell wall is impaired. These results show that different steps of sexual development are differentially regulated by the exocyst and suggest the existence of exocyst subcomplexes with distinct roles in mating.
Mohammad Reza Sharifmoghadam, Nagore de Leon, Marta Hoya, María-Angeles Curto, María-Henar Valdivieso. Different steps of sexual development are differentially regulated by the Sec8p and Exo70p exocyst subunits. FEMS microbiology letters. 2010 Apr;305(1):71-80
PMID: 20180855
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