What is an immunological synapse?

José Luis Rodríguez-Fernández, Lorena Riol-Blanco, Cristina Delgado-Martín

Centro de Investigaciones Biológicas, Consejo Superior de Investigaciones Científicas, 28040 Madrid, Spain. rodrifer@cib.csic.es

Microbes and infection / Institut Pasteur 2010 Jun

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Immunological synapses (IS) are emerging as highly organized 3D structures -formed by surface and cytoplasmic signalling and cytoskeletal molecules - that assemble at the zone of contact between a T cell and an antigen presenting cell (APC). The IS control functions that allow APC and T cells modulate the immune response. Copyright 2010 Elsevier Masson SAS. All rights reserved.

Citation

José Luis Rodríguez-Fernández, Lorena Riol-Blanco, Cristina Delgado-Martín. What is an immunological synapse? Microbes and infection / Institut Pasteur. 2010 Jun;12(6):438-45