Good clinical response to methotrexate treatment in a patient with fibroblastic rheumatism.

Fibroblastic rheumatism (FR) is a rare disease first described by Chaouat (in Rev Rhum Mal Osteoartic 47:345-351, 1980) and is characterized by a combination of rheumatologic and dermatological manifestations. Rheumatologic features are symmetrical polyarthralgias with joint stiffness, associated with cutaneous nodules and sclerodactyly. Histology shows an increased number of fibroblasts and a marked dermal fibrosis. A large number of treatments have been tried, but all of them have shown an unpredictable effect on FR. We report a Brazilian case of FR showing a good clinical response to methotrexate treatment. This drug may be considered an effective treatment in FR.

Citation

Juliane Aline Paupitz, Jozélio Freire de Carvalho. Good clinical response to methotrexate treatment in a patient with fibroblastic rheumatism. Rheumatology international. 2012 Jun;32(6):1789-91

PMID: 20340022

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