Ke Wang, Xiang-Yan Li, Xiao-Guang Chen, Zhan-Zhu Liu
Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine (Ministry of Education), Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Journal of Asian natural products research 2010 JanA series of novel bisindolylmaleimide and natural amino acid ester conjugates were synthesized and evaluated for their inhibitory activity against six tumor cell lines. Some compounds displayed interesting cytotoxic profiles. The most active compound 8e showed inhibitory activity against several human cancer cell lines.
Ke Wang, Xiang-Yan Li, Xiao-Guang Chen, Zhan-Zhu Liu. Synthesis and antitumor activity of bisindolylmaleimide and amino acid ester conjugates. Journal of Asian natural products research. 2010 Jan;12(1):36-42
PMID: 20390741
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