Cerebral hemorrhage associated with phenylpropanolamine].

O A Strand, S Lund-Tønnesen, O Sortland

Medisinsk avdeling, Sentralsykehuset i Akershus, Nordbyhagen.

Tidsskrift for den Norske lægeforening : tidsskrift for praktisk medicin, ny række 1991 May 10

filter terms:

In recent years, sympathomimetic drugs, including ephedrine, amphetamine and phenylpropanolamine, have been increasingly associated with cerebral haemorrhage and infarction. We report a case of intracranial bleeding in a 37 year-old woman with mononucleosis who took therapeutic doses of phenylpropanolamine. Cerebral CT on admission showed a left-sided intracerebral hematoma. Angiography was normal. Late bleeding occurred on the fourth day. She survived but developed a right-sided cerebral infarction with persistent epilepsy. Her mononucleosis was of moderate severity without bleeding diastesis. We conclude that the intracranial bleedings were secondary to taking phenylpropanolamine.

Citation

O A Strand, S Lund-Tønnesen, O Sortland. Cerebral hemorrhage associated with phenylpropanolamine]. Tidsskrift for den Norske lægeforening : tidsskrift for praktisk medicin, ny række. 1991 May 10;111(12):1490-2