The role of secondary structure in protein structure selection.

Yong-Yun Ji, You-Quan Li

Department of Physics, Wenzhou University, 325035 Wenzhou, PR China. yyji@wzu.edu.cn

The European physical journal. E, Soft matter 2010 May

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The presence of highly regular secondary structure motifs in protein structure is a fascinating area of study. The secondary structures play important roles in protein structure and protein folding. We investigate the folding properties of protein by introducing the effect of secondary structure elements. We observed the emergence of several structures with both large average energy gap and high designability. The dynamic study indicates that these structures are more foldable than those without the effect of secondary structures.

Citation

Yong-Yun Ji, You-Quan Li. The role of secondary structure in protein structure selection. The European physical journal. E, Soft matter. 2010 May;32(1):103-7