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In this prospective study, we analyzed 30 male infants with increased neonatal 17-hydroxyprogesterone (17OH-P) (patients) and for comparison 52 age-matched healthy babies (control subjects) with the aim of investigating the hypothalamic-pituitary-testis axis in the first 6 months of life. Although T, FSH, and LH levels were not significantly different in patients and control subjects, inhibin B was higher in patients than in control subjects. Therefore we suggest a clinical follow-up of these babies during childhood and puberty to verify the evolution of their condition. Copyright © 2010 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.


Paolo Cavarzere, Monica Vincenzi, Rossella Gaudino, Roberto Franceschi, Silvia Perlini, Marta Camilot, Francesca Teofoli, Franco Antoniazzi, Luciano Tatò. Possible andrologic markers in elevated neonatal 17-hydroxyprogesterone. Fertility and sterility. 2010 Nov;94(6):2350-2

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PMID: 20537623

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