Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine (Ministry of Education), Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, People's Republic of China.
European journal of medicinal chemistry 2010 SepA novel series of N-methylbisindolylmaleimides derivatives bearing 2-acetamino acid moieties were synthesized. The cytotoxic activities of these compounds were tested in six tumor cell lines. The most potent compound 8d displayed cytotoxicity against six human tumor cell lines in the micromolar range. 2010 Elsevier Masson SAS. All rights reserved.
Ke Wang, Zhan-Zhu Liu. Synthesis of N-methyl-bisindolylmaleimide amino acid methyl ester conjugates and cytotoxicity study. European journal of medicinal chemistry. 2010 Sep;45(9):4175-9
PMID: 20598779
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