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Disabled-1 is a key signaling molecule in the Reelin pathway that plays a critical role in neuronal migration and positioning during brain development. In this issue of Neuron, Yano et al. demonstrate that the neuron-specific RNA binding protein Nova2 contributes to neuronal migration by regulating alternative splicing of disabled-1.

Citation

Tae-Ju Park, Tom Curran. Alternative splicing disabled by Nova2. Neuron. 2010 Jun 24;66(6):811-3


PMID: 20620865

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