First detection of oxacillinase-mediated resistance to carbapenems in Klebsiella pneumoniae from Morocco.

A Benouda, O Touzani, M-T Khairallah, G F Araj, G M Matar

Hôpital International Cheikh Zaid, Madinat Al Irfane, Hay Riad, Rabat, Morocco.

Annals of tropical medicine and parasitology 2010 Jun

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The frequency of carbapenem resistance due to class-D beta-lactamases (i.e. oxacillinases) among the world's Enterobacteriaceae is increasing. Recently, in Morocco, two isolates of carbapenem-resistant Klebsiella pneumoniae were recovered from the same patient, one harbouring plasmid-encoded bla-(OXA-48) and the other the bla-(OXA-1) gene. This represents the first evidence of bla(OXA-48)-mediated carbapenem-resistance in Enterobacteriaceae in Morocco.

Citation

A Benouda, O Touzani, M-T Khairallah, G F Araj, G M Matar. First detection of oxacillinase-mediated resistance to carbapenems in Klebsiella pneumoniae from Morocco. Annals of tropical medicine and parasitology. 2010 Jun;104(4):327-30