Yin Qiang, Yan-Jun Chen, Ya Li, Jing Zhao, Kun Gao
State Key Laboratory of Applied Organic Chemistry and College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, Gansu, People's Republic of China.
Planta medica 2011 JanPhytochemical investigation of Gerbera saxatilis (Astraceae) afforded three new coumarin derivatives 1- 3 and a known coumarin 4. Compounds 1 and 2 represent the first examples of the natural occurrence of the novel polycyclic pyrano[3-2c]coumarin carbon skeleton. The structures of compounds 1- 4 were characterized based on extensive spectroscopic analyses as well as comparison to the spectroscopic data reported. The structures of compounds 1 and 3 were further confirmed by X-ray data analyses. The cytotoxic activity of compounds 1- 4 was evaluated against selected cancer cell lines, including human leukemia cell (HL-60), human hepatoma cell (SMMC-7721), and human cervical carcinoma cell (HeLa) lines. © Georg Thieme Verlag KG Stuttgart · New York.
Yin Qiang, Yan-Jun Chen, Ya Li, Jing Zhao, Kun Gao. Coumarin derivatives from Gerbera saxatilis. Planta medica. 2011 Jan;77(2):175-8
PMID: 20669089
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