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Anions cannot diffuse passively through biological membranes and membrane-bound proteins mainly govern the transmembrane movement of these charged species. The use of synthetic compounds that are able to facilitate the transmembrane transport of anions is a fascinating and burgeoning topic. The study of facilitated anion transport across lipid bilayers is an emerging field in supramolecular and bioorganic chemistry. In this critical review we describe the recent research progress in this area, focusing on literature published during the years 2007-2009. An overview of the assays that are used in the transmembrane transport of anions is also included (158 references).


Jeffery T Davis, Oluyomi Okunola, Roberto Quesada. Recent advances in the transmembrane transport of anions. Chemical Society reviews. 2010 Oct;39(10):3843-62

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PMID: 20820462

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