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We report a 45-year-old female patient with muscle weakness. We diagnosed renal tubular acidosis type I by laboratory findings of hypopotassemia, hypopotassuria, metabolic acidosis and basic urine. The muscle weakness improved rapidly by substitution of potassium and an alcalescent substance. Searching for associated autoimmune diseases we diagnosed primary biliary cirrhosis and initiated a therapy with ursodeoxycholic acid.


U Sieprath, M Lampen, C Firschke. 45-year-old woman with muscle weakness and hypopotassemia]. Der Internist. 2011 Apr;52(4):441-4

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PMID: 20941474

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