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Iron(III) chloride hexahydrate promotes a cascade of transformations on a Petasis condensation product that sets up the right dihydropyran precursors of valuable Relenza congeners.

Citation

Jean-François Soulé, Aurélie Mathieu, Stéphanie Norsikian, Jean-Marie Beau. Coupling the Petasis condensation to an iron(III) chloride-promoted cascade provides a short synthesis of Relenza congeners. Organic letters. 2010 Nov 19;12(22):5322-5

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PMID: 20945892

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