Inactivation of Ascaris suum by short-chain fatty acids.

Michael A Butkus, Kelly T Hughes, Dwight D Bowman, Janice L Liotta, Michael B Jenkins, Michael P Labare

Department of Geography and Environmental Engineering, US Military Academy, West Point, New York 10996, USA.

Applied and environmental microbiology 2011 Jan

filter terms:

Ascaris suum eggs were inactivated in distilled water and digested sludge by butanoic, pentanoic, and hexanoic acids. The fatty acids (short-chain fatty acids [SCFA]) were effective only when protonated and at sufficient concentrations. The conjugate bases were not effective at the concentrations evaluated. Predictions from an inhibition model (50% inhibitory concentration [IC(50)]) based on quantitative structure-activity relationships were congruent with inactivation data.

Citation

Michael A Butkus, Kelly T Hughes, Dwight D Bowman, Janice L Liotta, Michael B Jenkins, Michael P Labare. Inactivation of Ascaris suum by short-chain fatty acids. Applied and environmental microbiology. 2011 Jan;77(1):363-6