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A copper-mediated cyclization reaction of hydrazine with enediynones providing pyrazolo[1,5-a]pyridines.
Hung-Chou Wu, Long-Chih Hwang, Ming-Jung Wu
Department of Medicinal and Applied Chemistry, Kaohsiung Medical University, Kaohsiung, Taiwan.
Organic & biomolecular chemistry 2011 Feb 7Sizes of these terms reflect their relevance to your search.
2,7-Disubstituted pyrazolo[1,5-a]pyridines were synthesized in good chemical yields by the reaction of enediynones with hydrazine, followed by addition of copper chloride. This reaction can tolerate many functional groups.
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Hung-Chou Wu, Long-Chih Hwang, Ming-Jung Wu. A copper-mediated cyclization reaction of hydrazine with enediynones providing pyrazolo[1,5-a]pyridines. Organic & biomolecular chemistry. 2011 Feb 7;9(3):670-2
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PMID: 21120244
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