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Two new boldine derivatives: the 3-thiocarbamateboldine (3) and the 2,9-O,O-diacetyl-3-thiocarbamateboldine (4) have been synthesized and their cytotoxicity evaluated.


Franz A Thomet, Pablo Pinyol, Joan Villena, Luis J Espinoza, Patricio G Reveco. Cytotoxic thiocarbamate derivatives of boldine. Natural product communications. 2010 Oct;5(10):1587-90

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PMID: 21121254

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