Takayuki Yakura, Ayaka Ozono, Kohei Morimoto
Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Sugitani, Toyama, Japan. yakura@pha.u-toyama.ac.jp
Chemical & pharmaceutical bulletin 2011A catalytic oxidation of p-alkoxyphenols was developed using tetrabutylammonium bromide (TBAB) and Oxone(®). The reaction of p-alkoxyphenol (1) with a catalytic amount of TBAB in the presence of Oxone(®) as a co-oxidant in acetonitrile-water (2 : 1) gave the corresponding p-quinone (2) in excellent yield without special treatment.
Takayuki Yakura, Ayaka Ozono, Kohei Morimoto. An efficient catalytic oxidation of p-Alkoxypenols to p-quinones using tetrabutylammonium bromide and oxone. Chemical & pharmaceutical bulletin. 2011;59(1):132-4
PMID: 21212563
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